Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.50 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843936 | 0.80 | SMN1; SMN2 (0.77) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| SCHEMBL9463623 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| SCHEMBL9463095 | 0.77 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| SCHEMBL28229524 | 0.77 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| SCHEMBL9463141 | 0.76 | SMN1; SMN2 (0.70) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| SCHEMBL2148218 | 0.76 | SMN1; SMN2 (0.70) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| SCHEMBL3408925 | 0.76 | SMN1; SMN2 (0.70) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| SCHEMBL190379 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| Benzene SCHEMBL9851028 | 0.74 | SMN1; SMN2 (0.68) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 | |
| SCHEMBL9047310 | 0.74 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMEN1TDP1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208224-A | Phosphorus containing compounds as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |