Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581032 | 0.88 | MAPT (0.46) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL9482631 | 0.85 | MAPT (0.56) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL9498739 | 0.84 | MAPT (0.69) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL23579964 | 0.84 | MAPT (0.49) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL9637744 | 0.82 | MAPT (0.68) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL9637754 | 0.82 | MAPT (0.53) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL9637757 | 0.82 | MAPT (0.53) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL11969793 | 0.81 | KMT2A (0.47) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL3337954 | 0.80 | MAPT (0.48) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL9655244 | 0.80 | MEN1 (0.59) | MAPTKMT2AMEN1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214189-A | N-(2-hydroxyethyl nitrate)-2,4,6,-trinitrobenzamide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-05-25 | — | — | US | disclosed |
| US-4665083-A | ANTIDEPRESSANT, ANTIEPILEPTIC, SPASMOLYTIC, ANTIPARKINSONIC | EGIS GYOGYSZERGYAR (HU) | 1987-05-12 | — | — | US | disclosed |