Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HMGCR | P04035 | 2/20 | 0.49 |
| ▸ | DHCR24 | Q15392 | 6/20 | 0.40 |
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | OSBP | P22059 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464323 | 1.00 | MEN1 (0.52) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL11418226 | 0.90 | MEN1 (0.50) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL11490959 | 0.89 | USP2 (0.65) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL9464748 | 0.89 | USP2 (0.65) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL9464083 | 0.89 | USP2 (0.65) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL9769614 | 0.86 | HMGCR (0.46) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL11412948 | 0.82 | MEN1 (0.50) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL11417246 | 0.82 | MEN1 (0.50) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL11418989 | 0.82 | MEN1 (0.50) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL11412207 | 0.81 | USP2 (0.47) | MEN1KMT2AUSP2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202891-A | ANOREXIGENIC AGENTS, ANTICHOLESTEROL AGENTS, INHIBITORS OF CELL GROWTH | PARISH, EDWARD J. | 1980-05-13 | — | — | US | claimed |
| US-5216015-A | Androstanes | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1993-06-01 | — | — | US | disclosed |
| US-4202891-A | ANOREXIGENIC AGENTS, ANTICHOLESTEROL AGENTS, INHIBITORS OF CELL GROWTH | PARISH, EDWARD J. | 1980-05-13 | — | — | US | disclosed |