Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.75 |
| ▸ | NQO2 | P16083 | 7/20 | 0.75 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.75 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.75 |
| ▸ | ESR1 | P03372 | 1/20 | 0.75 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | P4HB | P07237 | 1/20 | 0.55 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | S100B | P04271 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465510 | 1.00 | PTGS1 (0.75) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL9465277 | 1.00 | PTGS1 (0.75) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL9465505 | 1.00 | PTGS1 (0.75) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL22383911 | 0.93 | NQO2 (0.76) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL31474400 | 0.93 | NQO2 (0.76) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL20457122 | 0.93 | NQO2 (0.76) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL375018 | 0.87 | ESR1 (1.00) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL9036145 | 0.87 | ESR1 (1.00) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL9036138 | 0.87 | ESR1 (1.00) | PTGS1NQO2PTGS2ESR2ESR1 | |
| SCHEMBL375017 | 0.87 | ESR1 (1.00) | PTGS1NQO2PTGS2ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198570-A | Aryloxyfluoroether esters, processes for preparation thereof, and alcohols and acids formed therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-30 | — | — | US | disclosed |