SCHEMBL9465485

SCHEMBL9465485

CC1(C)[C@]2(O)[C@H](n3ccc(=O)[nH]c3=O)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@]12O

nearest known ligand 0.70

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 16/20 0.70
P2RY4 P51582 11/20 0.70
POLA1 P09884 1/20 0.61
P2RY6 Q15077 7/20 0.54
P2RY14 Q15391 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5034568 0.85 P2RY2 (0.66) P2RY2P2RY4POLA1P2RY6
SCHEMBL14946253 0.83 P2RY2 (1.00) P2RY2P2RY4POLA1P2RY6P2RY14
SCHEMBL1979436 0.83 P2RY2 (1.00) P2RY2P2RY4POLA1P2RY6P2RY14
SCHEMBL14853738 0.83 P2RY2 (1.00) P2RY2P2RY4POLA1P2RY6P2RY14
SCHEMBL14853792 0.83 P2RY2 (1.00) P2RY2P2RY4POLA1P2RY6P2RY14
SCHEMBL17972338 0.83 P2RY2 (1.00) P2RY2P2RY4POLA1P2RY6P2RY14
SCHEMBL16368333 0.83 P2RY2 (1.00) P2RY2P2RY4POLA1P2RY6P2RY14
SCHEMBL19558286 0.83 P2RY2 (1.00) P2RY2P2RY4POLA1P2RY6P2RY14
SCHEMBL21006621 0.83 P2RY2 (1.00) P2RY2P2RY4POLA1P2RY6P2RY14
SCHEMBL30848947 0.83 P2RY2 (0.70) P2RY2P2RY4POLA1P2RY6P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed