SCHEMBL9465617

SCHEMBL9465617

CCCCCCCSc1ncnc2nc[nH]c12

nearest known ligand 0.97

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PAK1 Q13153 1/20 0.97
NPC1 O15118 3/20 0.59
LMNA P02545 3/20 0.59
RAB9A P51151 3/20 0.59
HTT P42858 2/20 0.59
TSHR P16473 2/20 0.57
TP53 P04637 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CDC7 O00311 4/20 0.56
DBF4 Q9UBU7 4/20 0.56
G6PD P11413 1/20 0.56
XDH P47989 1/20 0.54
MAPT P10636 1/20 0.53
CYP2C19 P33261 1/20 0.53
HIF1A Q16665 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8642694 1.00 PAK1 (0.97) PAK1NPC1LMNARAB9AHTT
SCHEMBL10927540 1.00 PAK1 (0.97) PAK1NPC1LMNARAB9AHTT
SCHEMBL1725584 0.98 PAK1 (1.00) PAK1NPC1LMNARAB9AHTT
SCHEMBL9443835 0.96 PAK1 (0.89) PAK1NPC1LMNARAB9AHTT
SCHEMBL2118558 0.89 PAK1 (0.82) PAK1NPC1LMNARAB9AHTT
SCHEMBL2115555 0.82 PAK1 (0.71) PAK1NPC1LMNARAB9AHTT
SCHEMBL31439407 0.82 PAK1 (0.71) PAK1NPC1LMNARAB9AHTT
SCHEMBL10435438 0.81 PAK1 (0.69) PAK1NPC1LMNARAB9AHTT
SCHEMBL10435430 0.80 PAK1 (0.68) PAK1NPC1LMNARAB9AHTT
SCHEMBL6747965 0.79 PAK1 (0.62) PAK1NPC1LMNARAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 US disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 EP disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 EP disclosed
US-20210403978-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-30 US disclosed
US-11149296-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-10-19 US disclosed
US-20200232005-A1 Methods of Producing and Using Single-Stranded Deoxyribonucleic Acids and Compositions for Use in Practicing the Same TAKARA BIO USA, INC. 2020-07-23 US disclosed
US-10584363-B2 Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same TAKARA BIO USA, INC. (US) 2020-03-10 US disclosed
US-20180100181-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-04-12 US disclosed
EP-3283638-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2018-02-21 EP disclosed
US-20170349927-A1 METHODS OF PRODUCING AND USING SINGLE-STRANDED DEOXYRIBONUCLEIC ACIDS AND COMPOSITIONS FOR USE IN PRACTICING THE SAME TAKARA BIO USA, INC. 2017-12-07 US disclosed
WO-2016168711-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-10-20 WO disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed
WO-1992020816-A1 DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF YALE UNIVERSITY (US) 1992-11-26 WO disclosed