Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466544 | 0.77 | CYP2D6 (0.37) | CYP2D6 | |
| SCHEMBL9484997 | 0.73 | CYP2D6 (0.34) | CYP2D6 | |
| Acetic Acid SCHEMBL9021378 | 0.73 | — | — | |
| Acetic Acid SCHEMBL9021793 | 0.69 | MAPT (0.33) | — | |
| Acetic Acid SCHEMBL9021992 | 0.68 | CYP1A2 (0.34) | — | |
| Acetic Acid SCHEMBL7464680 | 0.67 | — | — | |
| Acetic Acid SCHEMBL7464682 | 0.67 | — | — | |
| Acetic Acid SCHEMBL9687960 | 0.67 | — | — | |
| Acetic Acid SCHEMBL10815245 | 0.67 | MAPT (0.31) | — | |
| Acetic Acid SCHEMBL10815246 | 0.67 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202315-A | Antiboiotic | LUCKY, LTD. (KR) | 1993-04-13 | — | — | US | disclosed |
| WO-1992008721-A1 | NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | LUCKY, LTD. (KR) | 1992-05-29 | — | — | WO | disclosed |
| EP-0397511-A2 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY, LTD. (KR) | 1990-11-14 | — | — | EP | disclosed |