Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.64 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.58 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279695 | 0.93 | NR1H2 (0.79) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL17279696 | 0.87 | NR1H2 (0.59) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL26109969 | 0.81 | NR1H2 (0.96) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL17574086 | 0.81 | NR1H2 (0.96) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL17279700 | 0.79 | NR1H2 (0.92) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL12228171 | 0.79 | NR1H2 (0.86) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL11187134 | 0.79 | NR1H2 (0.86) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL15007066 | 0.79 | NR1H2 (0.64) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL17253717 | 0.79 | NR1H2 (0.92) | NR1H2NR1H3LMNANPC1RAB9A | |
| SCHEMBL28221056 | 0.79 | NR1H2 (0.63) | NR1H2NR1H3LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245043-A | Polyethers, polytriazoles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-09-14 | — | — | US | claimed |
| US-5182356-A | Reaction of di(hydroxyphenyl)-1,2,4-triazole monomers with activated aromatic dihalide or dinitro compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-01-26 | — | — | US | claimed |
| US-5245043-A | Polyethers, polytriazoles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-09-14 | — | — | US | disclosed |
| US-5245043-A | Polyethers, polytriazoles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-09-14 | — | — | US | disclosed |
| US-5182356-A | Reaction of di(hydroxyphenyl)-1,2,4-triazole monomers with activated aromatic dihalide or dinitro compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-01-26 | — | — | US | disclosed |
| US-5182356-A | Reaction of di(hydroxyphenyl)-1,2,4-triazole monomers with activated aromatic dihalide or dinitro compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-01-26 | — | — | US | disclosed |