Methenamine

Methenamine

SCHEMBL9467271

C/C=C/Cc1ccccc1.C1N2CN3CN1CN(C2)C3

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.54
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ARG2 P78540 1/20 0.42
HIF1A Q16665 1/20 0.41
MAPK1 P28482 1/20 0.40
TOP1 P11387 1/20 0.40
ATP4A P20648 1/20 0.36
ATP4B P51164 1/20 0.36
EPHX1 P07099 1/20 0.35
IDO1 P14902 1/20 0.35
CYP2D6 P10635 1/20 0.35
KCNH2 Q12809 2/20 0.35
TP53 P04637 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.34
SIGMAR1 Q99720 2/20 0.34
AGXT P21549 1/20 0.34
TAAR1 Q96RJ0 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2938308 0.87 MAOB (0.70) MAOBCA1CA2ARG2TOP1
SCHEMBL40701 0.87 MAOB (0.70) MAOBCA1CA2ARG2TOP1
Benzene SCHEMBL1226362 0.87 MAOB (0.70) MAOBCA1CA2ARG2TOP1
Benzene SCHEMBL1226361 0.87 MAOB (0.70) MAOBCA1CA2ARG2TOP1
SCHEMBL105172 0.87 MAOB (0.70) MAOBCA1CA2ARG2TOP1
Butane SCHEMBL28785258 0.81 MAOB (0.61) MAOBCA1CA2ARG2TOP1
Bicarbonate SCHEMBL32684914 0.79 MAOB (0.58) MAOBCA1CA2ARG2HIF1A
SCHEMBL15466749 0.72 MAOB (0.61) MAOBCA1CA2ARG2MAPK1
SCHEMBL15466750 0.72 MAOB (0.61) MAOBCA1CA2ARG2MAPK1
SCHEMBL1524697 0.72 MAOB (1.00) MAOBCA1CA2ARG2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5221491-A TWO-CYCLE OIL ADDITIVE EXXON CHEMICAL PATENTS INC. (US) 1993-06-22 US disclosed