Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360474 | 0.90 | TDP1 (0.38) | TDP1 | |
| SCHEMBL1876097 | 0.83 | BACE1 (0.31) | — | |
| SCHEMBL2948345 | 0.82 | KDM4E (0.34) | — | |
| SCHEMBL3734914 | 0.81 | GAA (0.44) | — | |
| SCHEMBL18595340 | 0.78 | — | — | |
| SCHEMBL2142592 | 0.78 | — | — | |
| SCHEMBL21379404 | 0.76 | MAPT (0.31) | — | |
| SCHEMBL28790081 | 0.76 | MAPT (0.31) | — | |
| SCHEMBL1085871 | 0.74 | MAPT (0.33) | TDP1 | |
| SCHEMBL15527157 | 0.74 | BACE1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252593-A | Hypotensive agents, cognition activators | GLAXO GROUP LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |