Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | PPM1B | O75688 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.52 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PPP5C | P53041 | 1/20 | 0.52 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105064 | 1.00 | KDM4E (0.52) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL9472368 | 1.00 | KDM4E (0.52) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL19619092 | 1.00 | KDM4E (0.52) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL18434862 | 1.00 | KDM4E (0.52) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL14354861 | 1.00 | KDM4E (0.52) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL10910890 | 1.00 | KDM4E (0.52) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL9699655 | 1.00 | KDM4E (0.52) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL283305 | 0.82 | KDM4E (0.37) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| Demethyl-Cantharidin SCHEMBL3195020 | 0.69 | TP53 (1.00) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| Demethyl-Cantharidin SCHEMBL9675442 | 0.69 | TP53 (1.00) | KDM4EGMNNPPM1BLMNAPPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245055-A | Multistage, ylide intermediate, treatment of thrombosis | E. R. SQUIBB & SONS, INC. (US) | 1993-09-14 | — | — | US | disclosed |
| US-5084387-A | Enzyme hydrolytic deesterification and cyclization | E. R. SQUIBB & SONS, INC. (US) | 1992-01-28 | — | — | US | disclosed |
| US-5084581-A | Hydrolysis with alkali metal carbonate, bicarbonate or hydroxide and cyclization | E. R. SQUIBB & SONS, INC. (US) | 1992-01-28 | — | — | US | disclosed |