SCHEMBL9468420

SCHEMBL9468420

O=C1c2ccc([N+](=O)[O-])cc2C(=O)N1c1cccc(N2C(=O)c3ccc([N+](=O)[O-])cc3C2=O)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 2/20 0.74
CA12 O43570 4/20 0.73
CA9 Q16790 3/20 0.73
CA1 P00915 2/20 0.73
CA2 P00918 2/20 0.73
TDP1 Q9NUW8 1/20 0.60
LPAR1 Q92633 1/20 0.57
LPAR5 Q9H1C0 1/20 0.57
LPAR3 Q9UBY5 1/20 0.57
HPN P05981 1/20 0.55
ALDH1A1 P00352 3/20 0.53
MAPT P10636 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
POLB P06746 1/20 0.53
CASP6 P55212 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PTPRC P08575 1/20 0.51
S100A4 P26447 1/20 0.51
ESR1 P03372 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10381359 0.95 SCN2A (0.82) SCN2ACA12CA9CA1CA2
SCHEMBL6581162 0.91 CA12 (0.67) SCN2ACA12CA9CA1CA2
SCHEMBL406359 0.90 CA12 (0.72) SCN2ACA12CA9CA1CA2
SCHEMBL28911681 0.90 CA12 (0.65) SCN2ACA12CA9CA1CA2
SCHEMBL9468302 0.88 SCN2A (0.63) SCN2ACA12CA9CA1CA2
SCHEMBL4234954 0.86 TDP1 (0.80) SCN2ACA12CA9CA1CA2
SCHEMBL11195176 0.86 CA12 (0.61) SCN2ACA12CA9CA1CA2
SCHEMBL11669113 0.85 SCN2A (1.00) SCN2ACA12CA9CA1CA2
SCHEMBL30758587 0.85 SCN2A (1.00) SCN2ACA12CA9CA1CA2
SCHEMBL9807401 0.84 CA12 (0.59) SCN2ACA12CA9CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117844291-A High-permeability leveling agent and preparation method thereof 宁波南海化学有限公司 2024-04-09 CN claimed
CN-117844291-A High-permeability leveling agent and preparation method thereof 宁波南海化学有限公司 2024-04-09 CN disclosed
US-20120082833-A1 Polyethermide resins useful for high temperature applications, and related processes GENERAL ELECTRIC COMPANY 2012-04-05 US disclosed
US-20120082833-A1 Polyethermide resins useful for high temperature applications, and related processes GENERAL ELECTRIC COMPANY 2012-04-05 US disclosed
US-20120081833-A1 ELECTRONIC DEVICES CONTAINING POLYETHERIMIDE COMPONENTS GENERAL ELECTRIC COMPANY (US) 2012-04-05 US disclosed
US-20120081833-A1 ELECTRONIC DEVICES CONTAINING POLYETHERIMIDE COMPONENTS GENERAL ELECTRIC COMPANY (US) 2012-04-05 US disclosed
US-5212277-A Engineering plastics KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-05-18 US disclosed