Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466179 | 0.96 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL5457352 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL5473974 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL5459507 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL5468192 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL466186 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL5462324 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL79031 | 0.94 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9818198 | 0.94 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL6417066 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP3A4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270383-A | Preparation of aqueous polyurethane dispersions | BASF AKTIENGESELLSCHAFT (DE) | 1993-12-14 | — | — | US | disclosed |