Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sucrose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.70 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sucrose SCHEMBL8854184 | 0.94 | CDK1 (0.63) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL936131 | 0.92 | CDK1 (0.73) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL3400014 | 0.91 | CDK1 (0.65) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL8922550 | 0.91 | CDK1 (0.68) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL15111439 | 0.91 | CDK1 (0.71) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL15111218 | 0.91 | CDK1 (0.71) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL5490627 | 0.91 | CDK1 (0.71) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL23690443 | 0.91 | CDK1 (0.82) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL23690724 | 0.91 | CDK1 (0.82) | CDK1CCNB1CA2CA9MEN1 | |
| Sucrose SCHEMBL24274201 | 0.91 | CDK1 (0.82) | CDK1CCNB1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019237728-A1 | COMPOSITION KIT FOR PREPARING POLYURETHANE FOAM AND PREPARATION METHOD AND APPLICATION THEREOF | 合肥华凌股份有限公司 | 2019-12-19 | — | — | WO | claimed |
| CN-108976463-A | It is used to prepare the composition suit and its preparation method and application of polyurethane foam | 合肥华凌股份有限公司 | 2018-12-11 | — | — | CN | claimed |
| CN-108976463-B | Composition set for preparing polyurethane foam, preparation method and application thereof | 合肥华凌股份有限公司 | 2021-01-26 | — | — | CN | disclosed |
| WO-2019237728-A1 | COMPOSITION KIT FOR PREPARING POLYURETHANE FOAM AND PREPARATION METHOD AND APPLICATION THEREOF | 合肥华凌股份有限公司 | 2019-12-19 | — | — | WO | disclosed |
| CN-108976463-A | It is used to prepare the composition suit and its preparation method and application of polyurethane foam | 合肥华凌股份有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-2439445-Y | Equipment for prepn. of polyether | UNIV HUANAN NORMAL (CN) | 2001-07-18 | — | — | CN | disclosed |
| US-5177116-A | Polysiloxane | BASF CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| US-5149725-A | Flexible polyurethane foams with reduced dripping during burning | BASF CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| US-4664563-A | SHORING UP GEOLOGICAL FORMATIONS | BASF CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |
| US-4614754-A | USING ALKOXYLATED TOLUENEDIAMINE POLYOL | BASF CORPORATION (US) | 1986-09-30 | — | — | US | disclosed |
| US-4025470-A | Process for the production of flame-resistant, hard polyurethane foams | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-24 | — | — | US | disclosed |