Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13429323 | 1.00 | LSS (0.57) | LSSCHRNA7SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3221930 | 0.88 | LSS (0.54) | LSSCHRNA7GLA | |
| SCHEMBL3221925 | 0.88 | LSS (0.54) | LSSCHRNA7GLA | |
| SCHEMBL13429315 | 0.87 | LSS (0.56) | LSSCHRNA7GLACHRM2CHRM1 | |
| SCHEMBL13495111 | 0.87 | LSS (0.53) | LSSCHRNA7CHRNA3GLACHRM2 | |
| SCHEMBL3215158 | 0.82 | LSS (0.78) | LSSCHRNA7GLA | |
| SCHEMBL3215152 | 0.82 | LSS (0.78) | LSSCHRNA7GLA | |
| Hydrochloric Acid SCHEMBL9469303 | 0.81 | LSS (0.76) | LSSCHRNA7GLA | |
| SCHEMBL3215247 | 0.80 | TSHR (0.56) | LSSSLC6A2SLC6A4SLC6A3GLA | |
| SCHEMBL3215242 | 0.80 | TSHR (0.56) | LSSSLC6A2SLC6A4SLC6A3GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258392-A | 3-quinuclidine derivatives | AKZO N.V. (NL) | 1993-11-02 | — | — | US | disclosed |
| EP-0497415-A1 | 3-Quinuclidine derivatives | Akzo Nobel N.V. (NL) | 1992-08-05 | — | — | EP | disclosed |