Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469217 | 0.94 | MEN1 (0.69) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL8582612 | 0.94 | MEN1 (0.64) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL9469445 | 0.91 | MEN1 (0.67) | MEN1TP53CYP1A2CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL9469603 | 0.89 | MEN1 (0.66) | MEN1TP53CYP1A2CYP2D6MAPT | |
| Fumaric Acid SCHEMBL9469589 | 0.88 | MEN1 (0.62) | MEN1TP53CYP1A2CYP2D6MAPT | |
| Fumaric Acid SCHEMBL9469594 | 0.88 | MEN1 (0.62) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL9469488 | 0.88 | MEN1 (0.70) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL9469386 | 0.85 | MEN1 (1.00) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL9468961 | 0.85 | MEN1 (1.00) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL9469286 | 0.85 | MEN1 (1.00) | MEN1TP53CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003415-A1 | PROTEIN KINASE C MODULATORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-03-05 | — | — | WO | claimed |
| US-5189046-A | Antiinflammatory agents, anticonvulsants | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| WO-1992003415-A1 | PROTEIN KINASE C MODULATORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |