Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469630 | 0.81 | CHRM2 (0.45) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9469096 | 0.81 | CHRM2 (0.45) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9469146 | 0.81 | CHRM2 (0.45) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9469800 | 0.81 | CHRM2 (0.45) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9469131 | 0.81 | CHRNA7 (0.48) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9469940 | 0.79 | GAA (0.51) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9469130 | 0.79 | CHRM2 (0.44) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9469753 | 0.79 | CHRM2 (0.44) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL4198496 | 0.79 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9469163 | 0.77 | SCD (0.43) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258392-A | 3-quinuclidine derivatives | AKZO N.V. (NL) | 1993-11-02 | — | — | US | disclosed |
| EP-0497415-A1 | 3-Quinuclidine derivatives | Akzo Nobel N.V. (NL) | 1992-08-05 | — | — | EP | disclosed |