Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.53 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1542299 | 0.84 | LSS (0.55) | LSSCHRNA7 | |
| SCHEMBL5390772 | 0.83 | LSS (0.60) | LSSCHRNA7 | |
| SCHEMBL3601115 | 0.82 | SLC6A2 (0.50) | LSS | |
| SCHEMBL9469406 | 0.82 | SLC6A2 (0.50) | LSS | |
| SCHEMBL1018531 | 0.81 | LSS (0.52) | LSSCHRNA7 | |
| SCHEMBL1721100 | 0.81 | LSS (0.46) | LSSCHRNA7 | |
| SCHEMBL1720624 | 0.81 | LSS (0.46) | LSSCHRNA7 | |
| SCHEMBL1019927 | 0.80 | LSS (0.51) | LSSCHRNA7 | |
| SCHEMBL1018942 | 0.80 | LSS (0.57) | LSSCHRNA7 | |
| SCHEMBL3215152 | 0.80 | LSS (0.78) | LSSCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258392-A | 3-quinuclidine derivatives | AKZO N.V. (NL) | 1993-11-02 | — | — | US | disclosed |
| EP-0497415-A1 | 3-Quinuclidine derivatives | Akzo Nobel N.V. (NL) | 1992-08-05 | — | — | EP | disclosed |