Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469687 | 1.00 | PPARG (0.53) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9469691 | 1.00 | PPARG (0.53) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9469160 | 0.97 | PPARG (0.49) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9470020 | 0.97 | PPARG (0.49) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9469666 | 0.97 | PPARG (0.49) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9469161 | 0.97 | PPARG (0.49) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9469966 | 0.97 | PPARG (0.49) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9469664 | 0.97 | PPARG (0.49) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9470015 | 0.97 | PPARG (0.49) | PPARGPPARAFAAHLMNAMAPT | |
| SCHEMBL9469963 | 0.97 | PPARG (0.49) | PPARGPPARAFAAHLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416069-B1 | NEW LEUCOTRIENE B 4 DERIVATIVES, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | claimed |
| US-5183925-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |