Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145862 | 1.00 | ACE (1.00) | ACE | |
| SCHEMBL10923181 | 1.00 | ACE (1.00) | ACE | |
| SCHEMBL11398819 | 0.89 | ACE (0.79) | ACE | |
| SCHEMBL10824345 | 0.88 | ACE (0.79) | ACE | |
| SCHEMBL10824344 | 0.88 | ACE (0.79) | ACE | |
| Hydrochloric Acid SCHEMBL10751493 | 0.86 | ACE (0.75) | ACE | |
| Hydrochloric Acid SCHEMBL10751499 | 0.86 | ACE (0.75) | ACE | |
| SCHEMBL10914374 | 0.84 | ACE (0.73) | ACE | |
| SCHEMBL10914377 | 0.84 | ACE (0.73) | ACE | |
| SCHEMBL11168035 | 0.84 | ACE (0.72) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200416-A | CYCLIC AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1993-04-06 | — | — | US | claimed |
| US-4595675-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-06-17 | — | — | US | disclosed |
| US-4251444-A | Thiazepino-[4,3-b]-isoquinoline-1,5-dione derivatives and precursors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |