Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.49 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.36 |
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308901 | 0.90 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL16234373 | 0.88 | SLC28A1 (0.51) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL28629420 | 0.86 | SLC28A1 (0.50) | SLC28A1SLC28A2SLC29A1SLC28A3TK1 | |
| SCHEMBL16385457 | 0.85 | SLC28A1 (0.48) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL9308676 | 0.85 | SLC28A1 (0.47) | SLC28A1SLC28A2SLC29A1SLC28A3TK1 | |
| SCHEMBL9310399 | 0.84 | SLC28A1 (0.52) | SLC28A1SLC28A2SLC29A1SLC28A3TK1 | |
| SCHEMBL9309902 | 0.84 | SLC28A1 (0.51) | SLC28A1SLC28A2SLC29A1SLC28A3TK1 | |
| SCHEMBL9225641 | 0.84 | SLC28A1 (0.51) | SLC28A1SLC28A2SLC29A1SLC28A3TK1 | |
| SCHEMBL9470725 | 0.82 | SLC28A1 (0.53) | SLC28A1SLC28A2SLC29A1SLC28A3TK1 | |
| SCHEMBL9470704 | 0.82 | SLC28A1 (0.47) | SLC28A1SLC28A2SLC29A1SLC28A3TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246931-A | Triazine-substituted cyclobutane derivatives; viricides; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5153352-A | Viricides and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |