Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.70 |
| ▸ | SQLE | Q14534 | 7/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14825999 | 1.00 | KMT2A (0.70) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL9474305 | 1.00 | KMT2A (0.70) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL9474310 | 1.00 | KMT2A (0.70) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11756512 | 0.92 | KMT2A (0.58) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11756517 | 0.92 | KMT2A (0.58) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL17919396 | 0.90 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23458541 | 0.87 | SQLE (0.65) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23477943 | 0.87 | SQLE (0.65) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL24885792 | 0.87 | SQLE (0.65) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23478018 | 0.87 | SQLE (0.65) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273969-A | A phosphonylmethylphosphoalkylaminoalkane derivative | E. R. SQUIBB & SONS, INC. (US) | 1993-12-28 | — | — | US | disclosed |
| US-5212164-A | Hypocholesterolemic and antiatherosclerotic agents | E. R. SQUIBB & SONS, INC. (US) | 1993-05-18 | — | — | US | disclosed |
| EP-0409181-A2 | Phosphorus-containing squalene synthetase inhibitors and method for their preparation | E.R. SQUIBB & SONS, INC. (US) | 1991-01-23 | — | — | EP | disclosed |