Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.60 |
| ▸ | ALOX5AP | P20292 | 9/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374708 | 0.99 | GPBAR1 (0.62) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9474610 | 0.87 | ALOX5AP (0.59) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9473998 | 0.85 | CYSLTR2 (0.57) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9123140 | 0.84 | CYSLTR1 (0.67) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9123411 | 0.84 | CYSLTR1 (0.67) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9122067 | 0.84 | CYSLTR1 (0.67) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9123403 | 0.84 | CYSLTR1 (0.67) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9121483 | 0.84 | CYSLTR1 (0.67) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9124616 | 0.83 | CYSLTR1 (0.68) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 | |
| SCHEMBL9124030 | 0.81 | CYSLTR1 (0.55) | GPBAR1CYSLTR1CYSLTR2ALOX5APALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192771-A | Lipoxygenase inhibitors as antiinflammatory agents | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-09 | — | — | US | claimed |