⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954205 | 0.93 | — | — | |
| SCHEMBL8954104 | 0.91 | — | — | |
| SCHEMBL9202734 | 0.91 | — | — | |
| SCHEMBL8954232 | 0.88 | — | — | |
| SCHEMBL9473226 | 0.85 | — | — | |
| SCHEMBL7269745 | 0.84 | — | — | |
| SCHEMBL8954142 | 0.83 | — | — | |
| SCHEMBL9474239 | 0.83 | — | — | |
| SCHEMBL9472975 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL8954322 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234917-A | Hypotensive agent, treatment of renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION | 1993-08-10 | — | — | US | disclosed |
| EP-0437103-A2 | Substituted 5-(alkyl)carboxamide imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-17 | — | — | EP | disclosed |