Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957386 | 0.84 | MEN1 (0.70) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL9152126 | 0.79 | KMT2A (0.56) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL1416011 | 0.79 | HPGD (0.61) | KMT2AMEN1SMN1; SMN2HPGDMAPT | |
| SCHEMBL4432503 | 0.77 | KMT2A (0.59) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL8846813 | 0.77 | MEN1 (0.56) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL8846821 | 0.77 | MEN1 (0.56) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL30310240 | 0.76 | MEN1 (0.71) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL1416416 | 0.75 | HPGD (0.56) | KMT2AMEN1SMN1; SMN2HPGDHTT | |
| SCHEMBL3038665 | 0.75 | SMN1; SMN2 (0.58) | KMT2ASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL2804467 | 0.75 | CA12 (0.52) | KMT2AMEN1CYP2C9ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | claimed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |