Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.62 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666105 | 0.92 | NPC1 (0.62) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL28755190 | 0.91 | NPC1 (0.65) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL28661257 | 0.91 | NPC1 (0.65) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL28942086 | 0.91 | NPC1 (0.65) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL28673232 | 0.91 | NPC1 (0.65) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL28755242 | 0.91 | NPC1 (0.65) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL18746216 | 0.89 | MEN1 (0.59) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL25222350 | 0.89 | HDAC6 (0.64) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL5821101 | 0.88 | NPC1 (0.57) | HDAC6HDAC1LTB4R2NPC1JAK2 | |
| SCHEMBL3482860 | 0.86 | LTB4R2 (0.56) | HDAC6HDAC1LTB4R2NPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110352192-B | Heterocyclic compound and harmful arthropod control agent containing same | 住友化学株式会社 | 2023-03-24 | — | — | CN | disclosed |
| CN-109843963-B | Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer | 旭化成株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-104891965-A | Environment-friendly building ceramic product | QINGDAO GUOHANG XIANGYU TECHNOLOGY SERVICE CO LTD | 2015-09-09 | — | — | CN | disclosed |
| CN-104402323-A | Building ceramic | QINGDAO KELIKE INFORMATION TECHNOLOGY CO LTD | 2015-03-11 | — | — | CN | disclosed |
| CN-102898990-A | Epoxy adhesive for ceramic bonding | SUZHOU FEN LAKE ELEVATOR CO | 2013-01-30 | — | — | CN | disclosed |
| CN-1123565-C | Process for preparing unsymmetric phenyl substituted urea | DALIAN CHEMICAL PHYSICS INST (CN) | 2003-10-08 | — | — | CN | disclosed |
| CN-1271725-A | Process for preparing unsymmetric phenyl substituted urea | DALIAN CHEMICAL PHYSICS INST (CN) | 2000-11-01 | — | — | CN | disclosed |
| US-5220061-A | Slowyly mixing n,n dialkyl-n-phenylurea and methylene bis/ alkyl carbamate/ with acid catalyst; heating | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1993-06-15 | — | — | US | disclosed |