Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475455 | 1.00 | HTT (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9475458 | 1.00 | HTT (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9475466 | 1.00 | HTT (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9475452 | 1.00 | HTT (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9478132 | 0.98 | CYP1A2 (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9478102 | 0.98 | CYP1A2 (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9478108 | 0.98 | CYP1A2 (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9478116 | 0.98 | CYP1A2 (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9478125 | 0.98 | CYP1A2 (0.38) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL9477394 | 0.93 | CYP1A2 (0.44) | HTTMEN1KMT2ACYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377469-B1 | A LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5183587-A | LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0377469-A1 | A liquid crystalline compound | CHISSO CORPORATION (JP) | 1990-07-11 | — | — | EP | disclosed |