Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 6/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476506 | 0.92 | MEN1 (0.46) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL9477260 | 0.92 | MEN1 (0.57) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL8554756 | 0.89 | MEN1 (0.61) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL8555655 | 0.88 | KCNH2 (0.55) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL9088726 | 0.87 | KCNH2 (0.54) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL9476946 | 0.86 | MEN1 (0.56) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL8557613 | 0.86 | KCNH2 (0.55) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL9473977 | 0.85 | POLB (0.55) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL9475193 | 0.85 | KCNH2 (0.50) | KCNH2HRH3MEN1KMT2ATOP2A | |
| SCHEMBL9089131 | 0.84 | KCNH2 (0.51) | KCNH2HRH3MEN1KMT2ATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908366-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | claimed |
| US-5190955-A | Bactericides, effective against antibiotic resistant germs | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5051418-A | Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| US-4908366-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |
| EP-0319906-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0276700-A1 | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |