Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802853 | 1.00 | MAPK1 (0.56) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL11001684 | 1.00 | MAPK1 (0.56) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL10975799 | 1.00 | MAPK1 (0.56) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL9475863 | 1.00 | MAPK1 (0.56) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL9178292 | 0.90 | CTDSP1 (0.51) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL10840102 | 0.90 | CTDSP1 (0.51) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL10840098 | 0.90 | CTDSP1 (0.51) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL9178288 | 0.90 | CTDSP1 (0.51) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL9479882 | 0.90 | CTDSP1 (0.51) | MAPK1ALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL9477097 | 0.90 | CTDSP1 (0.55) | MAPK1ALDH1A1HSD17B10KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266691-A | Processes for making cephems from allenylazetidinone derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-11-30 | — | — | US | disclosed |
| US-5162524-A | Antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5043439-A | Alkylation; organo-copper reagents; 3-hydrocarbon substitution ; antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |
| US-4060688-A | Cephalosporin intermediates | ELI LILLY AND COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4044002-A | ACYL BROMIDES AND A BROMINE SCAVENGER | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4017488-A | Process for preparing 7β-acylamino-7α-alkoxycephalosporins | SANKYO COMPANY LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |