Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9485329 | 0.99 | HTT (0.52) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL9476339 | 0.98 | HTT (0.53) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9476013 | 0.96 | HTT (0.52) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL8663227 | 0.93 | HTT (0.55) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8662185 | 0.91 | HTT (0.54) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL30982433 | 0.88 | HTT (0.53) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL30982430 | 0.88 | HTT (0.53) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL30983025 | 0.88 | HTT (0.53) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL30887389 | 0.87 | HTT (0.58) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL9700018 | 0.85 | HTT (0.53) | HTTSMN1; SMN2MEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256676-A | 3-hydroxy-pyridin-4-ones useful for treating parasitic infections | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1993-10-26 | — | — | US | disclosed |