SCHEMBL9477173

SCHEMBL9477173

CCCCCC1CCC(c2ccc(/C=C/F)cc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.43
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
SPHK1 Q9NYA1 11/20 0.40
ESR2 Q92731 2/20 0.39
GAA P10253 1/20 0.38
SPHK2 Q9NRA0 7/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9477190 1.00 CYP2C9 (0.43) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9477180 1.00 CYP2C9 (0.43) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9477714 0.99 SPHK1 (0.43) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9477723 0.99 SPHK1 (0.43) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9477730 0.99 SPHK1 (0.43) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9477185 0.96 CYP2C9 (0.43) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9477168 0.96 CYP2C9 (0.43) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9477176 0.96 CYP2C9 (0.43) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9476181 0.90 CYP2C9 (0.52) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9476172 0.90 CYP2C9 (0.52) CYP2C9MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377469-B1 A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5183587-A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-02-02 US disclosed
EP-0377469-A1 A liquid crystalline compound CHISSO CORPORATION (JP) 1990-07-11 EP disclosed