Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 15/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 15/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477489 | 1.00 | CYP11B1 (0.44) | CYP11B1CYP11B2RARBTSHRHSD17B10 | |
| SCHEMBL9477282 | 1.00 | CYP11B1 (0.44) | CYP11B1CYP11B2RARBTSHRHSD17B10 | |
| SCHEMBL9477475 | 1.00 | CYP11B1 (0.44) | CYP11B1CYP11B2RARBTSHRHSD17B10 | |
| SCHEMBL9477672 | 0.99 | CYP11B1 (0.45) | CYP11B1CYP11B2RARBRARARARG | |
| SCHEMBL9477652 | 0.99 | CYP11B1 (0.45) | CYP11B1CYP11B2RARBRARARARG | |
| SCHEMBL9477810 | 0.95 | CYP11B1 (0.46) | CYP11B1CYP11B2TRPV4KCNJ1 | |
| SCHEMBL9477822 | 0.95 | CYP11B1 (0.46) | CYP11B1CYP11B2TRPV4KCNJ1 | |
| SCHEMBL9477164 | 0.89 | CYP11B1 (0.48) | CYP11B1CYP11B2TRPV4KCNJ1 | |
| SCHEMBL9477145 | 0.89 | CYP11B1 (0.48) | CYP11B1CYP11B2TRPV4KCNJ1 | |
| SCHEMBL9478357 | 0.83 | RARB (0.46) | CYP11B1CYP11B2RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377469-B1 | A LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5183587-A | LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0377469-A1 | A liquid crystalline compound | CHISSO CORPORATION (JP) | 1990-07-11 | — | — | EP | disclosed |