Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477412 | 1.00 | ESR2 (0.36) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9477389 | 1.00 | ESR2 (0.36) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9477420 | 1.00 | ESR2 (0.36) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9476557 | 0.99 | ESR2 (0.36) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9476551 | 0.99 | ESR2 (0.36) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9476565 | 0.99 | ESR2 (0.36) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9476545 | 0.99 | ESR2 (0.36) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9478129 | 0.96 | ESR2 (0.34) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9478110 | 0.96 | ESR2 (0.34) | ESR2CCR2HTR2AHTR2CHTR2B | |
| SCHEMBL9478117 | 0.96 | ESR2 (0.34) | ESR2CCR2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377469-B1 | A LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5183587-A | LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0377469-A1 | A liquid crystalline compound | CHISSO CORPORATION (JP) | 1990-07-11 | — | — | EP | disclosed |