SCHEMBL9478166

SCHEMBL9478166

F/C=C/CCCC[C@H]1CC[C@H](CC[C@H]2CC[C@H](c3ccc(F)c(F)c3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.33
CCR2 P41597 1/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
USP5 P45974 2/20 0.32
USP30 Q70CQ3 1/20 0.32
KDM1A O60341 2/20 0.31
MAOB P27338 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
OPRL1 P41146 2/20 0.30
SGPL1 O95470 2/20 0.30
S1PR1 P21453 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9478184 1.00 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9478176 1.00 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9478188 1.00 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9477735 0.99 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9476618 0.99 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9477720 0.99 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9477712 0.99 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9476621 0.99 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9476610 0.99 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9476601 0.99 ESR2 (0.33) ESR2CCR2HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377469-B1 A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5183587-A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-02-02 US disclosed