Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478406 | 1.00 | GRIA1 (0.37) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9478405 | 1.00 | GRIA1 (0.37) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9477414 | 0.95 | GRIA1 (0.39) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9477411 | 0.95 | GRIA1 (0.39) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9477421 | 0.95 | GRIA1 (0.39) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9475718 | 0.91 | HRH3 (0.42) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9475721 | 0.91 | HRH3 (0.42) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9475715 | 0.91 | HRH3 (0.42) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9510390 | 0.87 | ESR2 (0.38) | GRIA1GRIA2GRIA3HSD11B1HDAC2 | |
| SCHEMBL9510387 | 0.87 | ESR2 (0.38) | GRIA1GRIA2GRIA3HSD11B1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377469-B1 | A LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5183587-A | LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0377469-A1 | A liquid crystalline compound | CHISSO CORPORATION (JP) | 1990-07-11 | — | — | EP | disclosed |