Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479286 | 1.00 | HDAC2 (0.35) | HDAC2KDM1AP2RY14CYP17A1CYP11B2 | |
| SCHEMBL9479289 | 1.00 | HDAC2 (0.35) | HDAC2KDM1AP2RY14CYP17A1CYP11B2 | |
| SCHEMBL9476670 | 0.89 | HTR2A (0.36) | HDAC2KDM1AMAOBHTR2AHTR2C | |
| SCHEMBL9476684 | 0.89 | HTR2A (0.36) | HDAC2KDM1AMAOBHTR2AHTR2C | |
| SCHEMBL9476664 | 0.89 | HTR2A (0.36) | HDAC2KDM1AMAOBHTR2AHTR2C | |
| SCHEMBL9311508 | 0.88 | CYP3A4 (0.35) | HDAC2KDM1AP2RY14CYP17A1CYP11B2 | |
| SCHEMBL9311501 | 0.88 | CYP3A4 (0.35) | HDAC2KDM1AP2RY14CYP17A1CYP11B2 | |
| SCHEMBL8963228 | 0.88 | P2RY14 (0.35) | HDAC2KDM1AP2RY14CYP17A1CYP11B2 | |
| SCHEMBL8381522 | 0.88 | CYP3A4 (0.35) | HDAC2KDM1AP2RY14CYP17A1CYP11B2 | |
| SCHEMBL8382880 | 0.88 | CYP3A4 (0.35) | HDAC2KDM1AP2RY14CYP17A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377469-B1 | A LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5183587-A | LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0377469-A1 | A liquid crystalline compound | CHISSO CORPORATION (JP) | 1990-07-11 | — | — | EP | disclosed |