Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715320 | 0.94 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL4134511 | 0.91 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL16949659 | 0.89 | TSHR (0.43) | TSHRHPGDSMPD1LMNATHRB | |
| SCHEMBL4957917 | 0.89 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL786290 | 0.89 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4SMPD1 | |
| SCHEMBL542079 | 0.89 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4SMPD1 | |
| SCHEMBL486802 | 0.89 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4SMPD1 | |
| SCHEMBL4951003 | 0.89 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4SMPD1 | |
| SCHEMBL4578058 | 0.89 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4SMPD1 | |
| SCHEMBL31520063 | 0.89 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244995-A | Vinyl halide aqueous polymerization dispersant system | THE BF GOODRICH COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5155189-A | Derived from repeating units of acrylic and/or methacrylic ester polymers | THE B. F. GOODRICH COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0483051-A1 | Improved vinyl halide aqueous polymerization dispersant system | The Geon Company (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4190693-A | WATERBASE, THERMOSETTING RESINS FOR DIRECT ROLL COATING | ROHM AND HAAS COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4126595-A | Aqueous coating compositions comprising acrylic oligomers, high molecular weight polymers and crosslinkers | ROHM AND HAAS COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4087397-A | Aqueous coating compositions comprising acrylic oligomers and high molecular weight polymers | ROHM AND HAAS COMPANY (US) | 1978-05-02 | — | — | US | disclosed |