Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | TACR1 | P25103 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21843055 | 1.00 | KMT2A (0.62) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL25032346 | 1.00 | KMT2A (0.62) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL29092265 | 0.89 | KMT2A (0.62) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL4385964 | 0.88 | CA1 (0.66) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL4382418 | 0.88 | CA1 (0.66) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL93708 | 0.88 | CA1 (0.66) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL93709 | 0.88 | CA1 (0.66) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL10591450 | 0.87 | KMT2A (0.60) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL19186293 | 0.85 | KMT2A (0.59) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL23297669 | 0.85 | KMT2A (0.59) | KMT2ACA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359290-B1 | AROMATIC DIOLS | GLAXO GROUP LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |
| US-5190967-A | Sexual dysfunction | GLAXO GROUP LIMITED (GB) | 1993-03-02 | — | — | US | disclosed |
| EP-0460912-A2 | Medicaments for the treatment of sexual disorder | GLAXO GROUP LIMITED (GB) | 1991-12-11 | — | — | EP | disclosed |
| US-5032603-A | Tranquilizers | GLAXO GROUP LIMITED (GB) | 1991-07-16 | — | — | US | disclosed |
| EP-0407016-A2 | Use of benzodioxinopyrrole derivatives in the manufacture of a medicament for the treatment of anxiety | GLAXO GROUP LIMITED (GB) | 1991-01-09 | — | — | EP | disclosed |
| EP-0162593-B1 | HETEROCYCLIC AMINO COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1990-08-16 | — | — | EP | disclosed |
| EP-0359290-A1 | Aromatic diols | GLAXO GROUP LIMITED (GB) | 1990-03-21 | — | — | EP | disclosed |
| EP-0162593-A1 | Heterocyclic amino compounds | GLAXO GROUP LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |