Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656762 | 1.00 | AR (0.64) | ARKCNH2 | |
| SCHEMBL5420574 | 0.85 | AR (0.58) | ARKCNH2 | |
| SCHEMBL9113552 | 0.80 | AR (0.64) | ARKCNH2 | |
| SCHEMBL14300609 | 0.80 | AR (0.64) | ARKCNH2 | |
| SCHEMBL9221841 | 0.80 | AR (0.64) | ARKCNH2 | |
| SCHEMBL4268107 | 0.80 | AR (0.62) | ARKCNH2 | |
| SCHEMBL13656783 | 0.80 | AR (0.62) | ARKCNH2 | |
| SCHEMBL13656800 | 0.80 | AR (0.64) | ARKCNH2 | |
| SCHEMBL13656798 | 0.80 | AR (0.69) | ARKCNH2 | |
| SCHEMBL4268103 | 0.80 | AR (0.62) | ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5237065-A | Steroid 5-alpha-reductase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0277002-B1 | STEROID-5-ALPHA-REDUCTASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5110939-A | Antiandrogens | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| US-4888336-A | DECREASE DIHYDROTESTOSTERONE ACTIVITY | SMITHKLINE BECKMAN CORPORATION (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0277002-A2 | Steroid-5-alpha-reductase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1988-08-03 | — | — | EP | disclosed |