Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472637 | 0.98 | HTT (0.53) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL9472440 | 0.98 | HTT (0.53) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL9472312 | 0.98 | HTT (0.53) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL9472094 | 0.98 | HTT (0.53) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL15977119 | 0.87 | KMT2A (0.49) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL12700005 | 0.87 | KMT2A (0.49) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL5936394 | 0.80 | HTT (0.49) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL14040806 | 0.80 | HTT (0.49) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL14537908 | 0.80 | HTT (0.49) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL14252032 | 0.80 | HTT (0.49) | HTTSMN1; SMN2KMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202350-A | Useful in inhibiting phospholipase A2 | BRISTOL-MYERS SQUIBB CO. (US) | 1993-04-13 | — | — | US | disclosed |