Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9484117

N.Nc1ccc(C(=O)Nc2ccc(S(=O)(=O)O)cc2)cc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.74
CA2 P00918 5/20 0.74
CA12 O43570 3/20 0.74
CA9 Q16790 3/20 0.74
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
POLB P06746 2/20 0.71
LMNA P02545 1/20 0.71
PKM P14618 1/20 0.71
APEX1 P27695 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
PRMT1 Q99873 4/20 0.67
SETD7 Q8WTS6 1/20 0.63
CASP6 P55212 1/20 0.61
CTDSP1 Q9GZU7 1/20 0.61
TIMP3 P35625 1/20 0.59
ALDH1A1 P00352 1/20 0.58
TSHR P16473 1/20 0.58
NT5E P21589 1/20 0.58
PTGS1 P23219 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2586732 0.98 CA1 (0.77) CA1CA2CA12CA9MEN1
SCHEMBL7454882 0.97 CA1 (0.74) CA1CA2CA12CA9MEN1
SCHEMBL28448504 0.90 CA1 (0.65) CA1CA2CA12CA9MEN1
SCHEMBL11859460 0.90 CA1 (0.70) CA1CA2CA12CA9MEN1
Sulfuric Acid SCHEMBL8638756 0.88 POLB (0.85) CA1CA2CA12CA9MEN1
SCHEMBL137276 0.84 POLB (1.00) CA1CA2CA12CA9MEN1
SCHEMBL30319980 0.84 POLB (1.00) CA1CA2CA12CA9MEN1
SCHEMBL9681496 0.84 POLB (1.00) CA1CA2CA12CA9MEN1
SCHEMBL2128727 0.84 POLB (1.00) CA1CA2CA12CA9MEN1
SCHEMBL1353478 0.84 POLB (1.00) CA1CA2CA12CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202436-A Dioxazine direct dyes BAYER AKTIENGESELLSCHAFT (DE) 1993-04-13 US disclosed