Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CALML3 | P27482 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482678 | 1.00 | GRM2 (0.53) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| SCHEMBL9482685 | 1.00 | GRM2 (0.53) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| SCHEMBL9482693 | 1.00 | GRM2 (0.53) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| SCHEMBL9484141 | 1.00 | GRM2 (0.53) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| SCHEMBL9463722 | 0.88 | GRM2 (0.57) | GRM2MAOB | |
| SCHEMBL9463584 | 0.88 | GRM2 (0.57) | GRM2MAOB | |
| SCHEMBL9463553 | 0.88 | GRM2 (0.57) | GRM2MAOB | |
| SCHEMBL9483405 | 0.88 | GRM2 (0.57) | GRM2MAOB | |
| SCHEMBL9482826 | 0.88 | GRM2 (0.57) | GRM2MAOB | |
| SCHEMBL9463172 | 0.88 | GRM2 (0.57) | GRM2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196543-A | Antidepressants, tranquilizers | DELALANDE S.A. (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5036091-A | Psychotropic drugs | DELALANDE S.A. (FR) | 1991-07-30 | — | — | US | disclosed |