Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428589 | 0.91 | S1PR1 (0.50) | S1PR1S1PR5S1PR4 | |
| SCHEMBL3431435 | 0.89 | S1PR1 (0.48) | S1PR1S1PR5S1PR4USP30 | |
| SCHEMBL949281 | 0.89 | S1PR1 (0.64) | S1PR1S1PR5S1PR4FFAR4 | |
| SCHEMBL3429408 | 0.87 | S1PR1 (0.46) | S1PR1S1PR5S1PR4 | |
| SCHEMBL3429957 | 0.86 | S1PR1 (0.46) | S1PR1S1PR5S1PR4 | |
| SCHEMBL3426893 | 0.84 | S1PR1 (0.42) | S1PR1S1PR5S1PR4 | |
| SCHEMBL947699 | 0.83 | S1PR1 (0.59) | S1PR1S1PR5S1PR4 | |
| SCHEMBL3431635 | 0.82 | S1PR1 (0.43) | S1PR1S1PR5S1PR4 | |
| SCHEMBL3423106 | 0.81 | S1PR1 (0.64) | S1PR1S1PR5S1PR4 | |
| SCHEMBL946682 | 0.80 | S1PR1 (0.44) | S1PR1S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005290-A1 | DISUBSTITUTED OXADIAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |