Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340810 | 1.00 | MEN1 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL9484781 | 1.00 | MEN1 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL9485533 | 1.00 | MEN1 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL9640129 | 1.00 | MEN1 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL9486045 | 1.00 | MEN1 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL8374332 | 1.00 | MEN1 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL9485458 | 1.00 | MEN1 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL9650375 | 1.00 | MEN1 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL8914105 | 0.93 | MEN1 (0.40) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL8018834 | 0.91 | MEN1 (0.38) | MEN1KMT2ANR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358741-B1 | DERIVATIVES OF 2,3-DIFLUOROBENZOIC ACID | MERCK PATENT GmbH (DE) | 1993-02-10 | — | — | EP | disclosed |
| EP-0332006-B1 | SMECTIC LIQUID-CRYSTAL COMPOSITION | MERCK PATENT GmbH (DE) | 1993-01-13 | — | — | EP | disclosed |
| EP-0332007-B1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK PATENT GmbH (DE) | 1992-11-25 | — | — | EP | disclosed |
| EP-0373186-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK PATENT GmbH (DE) | 1990-06-20 | — | — | EP | disclosed |
| EP-0362317-A1 | SMECTIC LIQUID CRYSTAL MEDIUM | MERCK PATENT GmbH (DE) | 1990-04-11 | — | — | EP | disclosed |
| EP-0358741-A1 | DERIVATIVES OF 2,3-DIFLUOROBENZOIC ACID. | MERCK PATENT GMBH (DE) | 1990-03-21 | — | — | EP | disclosed |
| WO-1989008690-A1 | SMECTIC LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989008688-A1 | DERIVATIVES OF 2,3-DIFLUOROBENZOIC ACID | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989008637-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| EP-0332006-A1 | Smectic liquid-crystal composition | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
| EP-0332007-A1 | Derivatives of 2,3-difluorohydroquinone | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |