Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485694 | 1.00 | GRIA1 (0.43) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL9326560 | 0.87 | GRIA1 (0.42) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL9326567 | 0.87 | GRIA1 (0.42) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL11618153 | 0.86 | GRIA2 (0.45) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL9450875 | 0.84 | GRIA1 (0.48) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL1658450 | 0.82 | MEN1 (0.56) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL261024 | 0.82 | MEN1 (0.56) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL9325765 | 0.82 | GRIA1 (0.41) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL9325768 | 0.82 | GRIA1 (0.41) | GRIA1GRIA2GRIA3MEN1MAPK1 | |
| SCHEMBL10832031 | 0.81 | MEN1 (0.55) | GRIA1GRIA2GRIA3MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252252-A | Longitudinal polarization | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-10-12 | — | — | US | disclosed |
| US-5230829-A | PHENYLCYCLOHEXANES, AND A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5120467-A | Longitudinal polarization and-or cross-polarization | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-06-09 | — | — | US | disclosed |
| EP-0478740-A1 | PHENYL CYCLOHEXANES AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GmbH (DE) | 1992-04-08 | — | — | EP | disclosed |
| WO-1991016291-A1 | PHENYL CYCLOHEXANES AND LIQUID CRYSTALLINE MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-10-31 | — | — | WO | disclosed |
| US-4723005-A | CONTAINING POLARIZED CYANO OR HALOGEN SUBSTITUENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0139996-B1 | ANISOTROPIC COMPOUNDS AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GmbH (DE) | 1987-11-04 | — | — | EP | disclosed |
| EP-0139996-A1 | Anisotropic compounds and liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1985-05-08 | — | — | EP | disclosed |