Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.69 |
| ▸ | RARB | P10826 | 4/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RARA | P10276 | 1/20 | 0.58 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485532 | 1.00 | PTPN11 (0.69) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL9484379 | 1.00 | PTPN11 (0.69) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL9484735 | 1.00 | PTPN11 (0.69) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL9485520 | 1.00 | PTPN11 (0.69) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL10340811 | 0.99 | PTPN11 (0.70) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL9485391 | 0.99 | PTPN11 (0.70) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL9640138 | 0.99 | PTPN11 (0.70) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL9486054 | 0.99 | PTPN11 (0.70) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL7875556 | 0.99 | PTPN11 (0.70) | PTPN11RARBTP53TSHRRARA | |
| SCHEMBL9485471 | 0.99 | PTPN11 (0.70) | PTPN11RARBTP53TSHRRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332006-B1 | SMECTIC LIQUID-CRYSTAL COMPOSITION | MERCK PATENT GmbH (DE) | 1993-01-13 | — | — | EP | disclosed |
| EP-0332007-B1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK PATENT GmbH (DE) | 1992-11-25 | — | — | EP | disclosed |
| EP-0373186-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK PATENT GmbH (DE) | 1990-06-20 | — | — | EP | disclosed |
| EP-0362317-A1 | SMECTIC LIQUID CRYSTAL MEDIUM | MERCK PATENT GmbH (DE) | 1990-04-11 | — | — | EP | disclosed |
| WO-1989008690-A1 | SMECTIC LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989008637-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| EP-0332007-A1 | Derivatives of 2,3-difluorohydroquinone | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
| EP-0332006-A1 | Smectic liquid-crystal composition | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |