Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 8/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487231 | 0.97 | MEN1 (0.38) | MEN1KMT2AAPPCYP2C9CYP3A4 | |
| SCHEMBL9487745 | 0.97 | MEN1 (0.38) | MEN1KMT2AAPPCYP2C9CYP3A4 | |
| SCHEMBL9486951 | 0.96 | APP (0.39) | MEN1KMT2AAPPCYP2C9CYP3A4 | |
| SCHEMBL9487572 | 0.95 | MEN1 (0.38) | MEN1KMT2AAPPCYP2C9CYP3A4 | |
| SCHEMBL9486418 | 0.94 | APP (0.39) | MEN1KMT2AAPPCYP2C9CYP3A4 | |
| SCHEMBL10723391 | 0.90 | MEN1 (0.41) | MEN1KMT2AAPPCYP2C9CYP3A4 | |
| SCHEMBL8678297 | 0.85 | AKR1C3 (0.43) | MEN1KMT2AAPPCYP2C9CYP3A4 | |
| SCHEMBL9485828 | 0.85 | MAPT (0.32) | MEN1KMT2ACYP2C9 | |
| SCHEMBL8678073 | 0.84 | AKR1C3 (0.40) | MEN1KMT2AAPPCYP2C9CYP3A4 | |
| SCHEMBL9485865 | 0.83 | KMT2A (0.43) | MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190692-A | FOUR RING ESTERS AND ETHERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |