Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488384 | 1.00 | MEN1 (0.42) | MEN1KMT2AITGB3ITGA2BTSHR | |
| SCHEMBL9486946 | 0.98 | MEN1 (0.42) | MEN1KMT2AITGB3ITGA2BTSHR | |
| SCHEMBL9487875 | 0.98 | MEN1 (0.42) | MEN1KMT2AITGB3ITGA2BTSHR | |
| SCHEMBL9485865 | 0.97 | KMT2A (0.43) | MEN1KMT2AITGB3ITGA2BTSHR | |
| SCHEMBL9487772 | 0.94 | KMT2A (0.43) | MEN1KMT2AITGB3ITGA2BTSHR | |
| SCHEMBL9486977 | 0.94 | KMT2A (0.40) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL2827604 | 0.93 | MEN1 (0.43) | MEN1KMT2AITGB3ITGA2BTSHR | |
| SCHEMBL2829785 | 0.86 | MEN1 (0.47) | MEN1KMT2AITGB3ITGA2BTSHR | |
| SCHEMBL4827223 | 0.86 | MEN1 (0.47) | MEN1KMT2AITGB3ITGA2BTSHR | |
| SCHEMBL7511859 | 0.85 | MEN1 (0.44) | MEN1KMT2ATSHRMAPTOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190692-A | FOUR RING ESTERS AND ETHERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |