Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | HAT1 | O14929 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25562783 | 0.87 | NPC1 (0.55) | NPC1RAB9AEPHB3ADORA2AGGPS1 | |
| SCHEMBL14743372 | 0.81 | NPC1 (0.63) | NPC1RAB9AEPHB3ADORA2AGGPS1 | |
| SCHEMBL3549382 | 0.81 | NPC1 (0.59) | NPC1RAB9AEPHB3ADORA2AGGPS1 | |
| Hydrochloric Acid SCHEMBL14746375 | 0.80 | NPC1 (0.61) | NPC1RAB9AEPHB3ADORA2AGGPS1 | |
| SCHEMBL496758 | 0.80 | NPC1 (0.60) | NPC1RAB9AEPHB3ADORA2AGGPS1 | |
| Hydrochloric Acid SCHEMBL21834227 | 0.78 | NPC1 (0.59) | NPC1RAB9AEPHB3ADORA2AGGPS1 | |
| SCHEMBL2017759 | 0.78 | NPC1 (0.59) | NPC1RAB9AEPHB3ADORA2ANPSR1 | |
| SCHEMBL9913664 | 0.77 | EPHB3 (0.62) | NPC1RAB9AEPHB3ADORA2ASMN1; SMN2 | |
| SCHEMBL14707153 | 0.77 | NPC1 (0.55) | NPC1RAB9AEPHB3ADORA2AGGPS1 | |
| SCHEMBL2498113 | 0.77 | NPC1 (0.55) | NPC1RAB9AEPHB3ADORA2AHAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1564213-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | HRH4, F2, HRH2 | NPC1 2889/4885RAB9A 3665/4885EPHB3 2147/4885 |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | F2, H1-3, CYC1 | NPC1 2969/4885RAB9A 3699/4885EPHB3 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.