Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 9/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717003 | 0.98 | MPL (0.40) | MPLRARBCHKAHSD11B1CTSL | |
| SCHEMBL12740084 | 0.98 | MPL (0.40) | MPLRARBCHKAHSD11B1CTSL | |
| SCHEMBL22131040 | 0.97 | MPL (0.41) | MPLRARBCHKAHSD11B1CTSL | |
| SCHEMBL9485788 | 0.95 | MPL (0.43) | MPLRARBCHKAHSD11B1CTSL | |
| SCHEMBL9485527 | 0.95 | RARB (0.45) | MPLRARBCHKAHSD11B1TYR | |
| SCHEMBL12994336 | 0.95 | MPL (0.40) | MPLRARBCHKAHSD11B1CTSL | |
| SCHEMBL12740085 | 0.94 | RARB (0.44) | MPLRARBCHKAHSD11B1TYR | |
| SCHEMBL9486110 | 0.94 | RARB (0.47) | RARBCHKAHSD11B1TYRALOX5 | |
| SCHEMBL9486681 | 0.94 | RARB (0.47) | RARBCHKAHSD11B1TYRALOX5 | |
| SCHEMBL9486821 | 0.94 | RARB (0.47) | RARBCHKAHSD11B1TYRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204019-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | claimed |
| EP-0362318-B1 | 2,3-DIFLUOROBIPHENYLS | MERCK PATENT GmbH (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-5204019-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |